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New Safety Standard for Baby Formula
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New Safety Standard for Baby Formula
12.02.08 U.S. officials adjust level of chemical melamine allowed in infant milk products
Best of the Web
12.01.08 Hits of the week
Fall Babies Face Higher Asthma Risk
12.01.08 Study cites cold and virus exposure
Children and Gratitude
11-27-08: My Greatest Blessing
Gestational Diabetes Tied to Language Delays
11.27.08 Study adds talking skills to long list of health issues linked to condition
Birth Defects Tied to Fertility Techniques
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Fetal Alcohol Syndrome
The Risks and Scares of Drinking Before You Know You're Pregnant
Baby's First Food
11.25.08 Baby's 29th Week
Baby Name Stirs Up Web Buzz
11.25.08 Celebrity couple's newborn joins group of little ones named after a city
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11.25.08 Age and symptoms are key in dealing with a high temp
Gifts for Mom and Baby
11.24.08 Our Holiday Gift Guide
Check out these great holiday gift ideas!

Stroller Design May Stress Out Baby
11.24.08 Front-facing style can impact a child's development, study says
Best of the Web
11.21.08 Hits of the week
Mother Guilt
11-20-08: What We Should or Shouldn't Be Doing
How to Install a Car Seat
Get a [professional] helping hand on installing your car seat
Anna Z and Ilya Lagutenko
Talk about a glam couple
Angelina Stops Breastfeeding
11.20.08: Brad gushes about fatherhood on "Oprah"
iPhone Apps Target New Parents
11.19.08 Features make a mom's job a little bit easier (and dad's, too!)
Missed Periods and Pregnancy Scares
Is It Too Early or Too Late?
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The genetics of birth timing: insights into a fundamental component of human development.
Authors: Chaudhari B, Plunkett J, Ratajczak C, Shen T, Defranco E, Muglia Lj The timing of birth necessitates the coupling of fetal maturation with the onset of parturition, and occurs at characteristic, but divergent gestations between mammals. Preterm birth in humans is an important but poorly understood outcome of pregnancy that uncouples fetal maturation and birth timing. The etiology of preterm birth is complex, involving environmental and genetic factors whose underlying molecular and cellular pathogenic mechanisms remain poorly understood. Animal models, although limited by differences with human physiology, have been crucial in exploring the role of various genetic pathways in mammalian birth timing. Studies in humans of both familial aggregation and racial disparities in prete...
Techniques can help ease irregular heart beat during pregnancy
Stuttgart, Germany - Women who experience an irregular heart beat during pregnancy can sometimes treat the problem themselves by (Source: Monsters and Critics Health News)
Pregnancy loss 'increases risk of drug and alcohol use'
Young women who have a miscarriage or an abortion are three times more likely to experience a drug or alcohol problem during their lifetime, according to new research published in the December issue of the British Journal of Psychiatry. Recent evidence has suggested that induced abortion may be associated with later psychiatric disorders in women. (Source: Health News from Medical News Today)
Cryobanks international, inc.: cryobanks international and becoming mom pregnancy spa & ultrasound imaging center team up to educate moms about umbilical cord blood
ALTAMONTE SPRINGS, FL (MARKET WIRE) Cryobanks International Inc., a leader in the collection, processing, and banking of umbilical cord blood, is pleased to announce its new partnership with Becoming Mom Pregnancy Spa & Imaging Center located in Mason, OH, a Cincinnati, OH suburb. (Source: Market Wire - Pharmaceuticals and Biotech)
Protease activated receptor-1, par1, promotes placenta trophoblast invasion and [beta]-catenin stabilization
Despite extensive efforts toward elucidation of the molecular pathway controlling cytotrophoblast (CTB) invasion to the uterine decidua, it remains poorly defined. There are striking similarities between tumor cell invasion and cytotrophoblast implantation to the deciduas whereby the role of Protease Activated Receptors (PARs) and wnt signaling is well recognized. We examine here consequences of modulation of PAR1 and PAR2 expression and function on CTB invasion and [beta]-catenin stabilization. Toward this end, we utilized a model system of extravillous trophoblast (EVT) organ culture and various placenta cell lines (e.g., JAR and HTR-8/Svneo). Activation of PAR1 induces EVT invasion while hPar1-SiRNA and PAR1 antagonist SCH79797 - effectively inhibited it. In parallel, the Wnt inhibitor ...
[papers] abortion and mental health disorders: evidence from a 30-year longitudinal study
Conclusions The evidence is consistent with the view that abortion may be associated with a small increase in risk of mental disorders. Other pregnancy outcomes were not related to increased risk of mental health problems. (Source: The British Journal of Psychiatry)
[papers] pregnancy loss and psychiatric disorders in young women: an australian birth cohort study
Conclusions These findings add to the growing body of evidence suggesting that pregnancy loss per se, whether abortion or miscarriage, increases the risk of a range of substance use disorders and affective disorders in young women. (Source: The British Journal of Psychiatry)
[correspondence] are antidepressants safe during pregnancy?
(Source: The British Journal of Psychiatry)
Maintenance nifedipine tocolysis compared with placebo: a randomized controlled trial.
CONCLUSION: When compared with placebo, maintenance nifedipine tocolysis did not confer a large reduction in preterm birth or improvement in neonatal outcomes. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, www.clinicaltrials.gov, NCT00185952 LEVEL OF EVIDENCE: I. PMID: 19037029 [PubMed - in process] (Source: Obstetrics and Gynecology)
Prevention of developmental delays in a down syndrome mouse model.
CONCLUSION: Prenatal treatment with NAPVSIPQ and SALLRSIPA prevented developmental delay and the glial deficit in Down syndrome. These findings highlight a possibility for the prevention of developmental sequelae in Down syndrome and suggest a potential intervention during pregnancy that may improve the outcome. PMID: 19037032 [PubMed - as supplied by publisher] (Source: Obstetrics and Gynecology)
A 12-month prospective evaluation of transcervical sterilization using implantable polymer matrices.
CONCLUSION: This transcervical sterilization system offers an effective contraceptive method, which was well tolerated and had a high satisfaction rate. LEVEL OF EVIDENCE: III. PMID: 19037035 [PubMed - as supplied by publisher] (Source: Obstetrics and Gynecology)
Fellowship training: the ever-changing subspecialty of maternal-fetal medicine.
CONCLUSION: The current scope of maternal-fetal medicine practice incorporates more ambulatory care than hospital-based care. Training programs rate highly in adequacy for high-risk pregnancy management and ultrasonography but lower in other aspects. LEVEL OF EVIDENCE: II. PMID: 19037038 [PubMed - in process] (Source: Obstetrics and Gynecology)
Long-term blood pressure changes measured from before to after pregnancy relative to nonparous women.
CONCLUSION: A first birth is accompanied by persistent lowering of blood pressure from preconception to years after delivery. Although the biologic mechanism is unclear, pregnancy may create enduring alterations in vascular endothelial function. LEVEL OF EVIDENCE: II. PMID: 19037039 [PubMed - as supplied by publisher] (Source: Obstetrics and Gynecology)
Two distinct oral routes of misoprostol in mifepristone medical abortion: a randomized controlled trial.
CONCLUSION: Buccal misoprostol 800 mcg after mifepristone 200 mg is a good option for medical abortion through 63 days since the LMP. Oral misoprostol 800 mcg is also a safe and effective alternative, although success rates diminish with increasing gestational age. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, www.clinicaltrials.gov, NCT00386867 LEVEL OF EVIDENCE: I. PMID: 19037040 [PubMed - as supplied by publisher] (Source: Obstetrics and Gynecology)
Prediction of location of a symptomatic early gestation based solely on clinical presentation.
CONCLUSION: A simplified scoring system based on five factors (age, ectopic history, bleeding, prior miscarriage, and human chorionic gonadotropin level) was as effective as a Classification and Regression Tree or logistic regression modes in predicting outcome of women at risk for ectopic pregnancy. Prediction of location of a symptomatic first-trimester pregnancy based on clinical symptoms and risk factors is possible, but must be used in conjunction with outpatient surveillance. LEVEL OF EVIDENCE: II. PMID: 19037042 [PubMed - in process] (Source: Obstetrics and Gynecology)
The ethics of randomized placebo-controlled trials of antidepressants with pregnant women: a systematic review.
CONCLUSION: Randomized placebo-controlled trials of antidepressant medications during pregnancy are ethically justified. Well-conducted and ethically justified trials of antidepressants should improve the quality of care provided to depressed pregnant women and thus address a major public health problem. PMID: 19037048 [PubMed - as supplied by publisher] (Source: Obstetrics and Gynecology)
Maternal thyroid hypofunction and pregnancy outcome.
Authors: Blumenfeld Z PMID: 19037051 [PubMed - in process] (Source: Obstetrics and Gynecology)
Down-regulation of hla-g boosted natural killer cell-mediated cytolysis in jeg-3 cells cultured in vitro
Conclusion(s): These results indicate that the recombinant adenoviral vectors used were efficient tools for studying HLA-G function. More important, this study reveals an important immunoprotective function for HLA-G in controlling NK cell-mediated lysis of trophoblasts, cells whose role in mediating normal pregnancy is important. (Source: Fertility and Sterility)
Basal follicle-stimulating hormone as a predictor of fetal aneuploidy
Conclusion(s): Our data do not support the hypothesis that an elevated basal FSH concentration is associated with an increase in fetal aneuploidy. Our findings suggest that the association between diminished ovarian reserve and SAB may result from nonkaryotypic factors. (Source: Fertility and Sterility)
Pregnancy after uterine fibroid embolization: follow-up of 100 patients embolized using tris-acryl gelatin microspheres
Conclusion(s): Despite the small sample size, uterine artery embolization appears to be viable in young women who still want to become pregnant. Larger series and studies comparing uterine fibroid embolization and myomectomy are needed. (Source: Fertility and Sterility)
Changes in blood-flow impedance of the human corpus luteum throughout the luteal phase and during early pregnancy
Conclusion(s): The change in luteal-RI was associated with corpus luteum development and corpus luteum regression. Luteal-RI was closely associated with luteal function. (Source: Fertility and Sterility)
Abdominal scar characteristics as a predictor of intra-abdominal adhesions at repeat cesarean delivery
Conclusion: A depressed abdominal scar of a previous cesarean delivery is correlated with the incidence and severity of intra-abdominal adhesions. (Source: Fertility and Sterility)
Sex chromosome characteristics and recurrent miscarriage
Conclusion(s): The frequency of both extremely and mildly skewed XCI was similar in patients and control women. Y chromosome microdeletions were not found in spouses of patients. Based on these results we conclude that skewed X inactivation and Y chromosome microdeletions are not associated with RM in our study couples. (Source: Fertility and Sterility)
Effects of polycystic ovarian syndrome on in vitro fertilization?embryo transfer outcomes are influenced by body mass index
Conclusion(s): Patients with PCOS with a body mass index (BMI) in the lean rather than the obese range have more favorable assisted reproductive technology (ART) cycle characteristics but show no clinical outcome differences. (Source: Fertility and Sterility)
Clinical use of colony-stimulating factor-1 in ovulation induction for poor responders
Conclusion(s): Concomitant administration of CSF-1 and hMG improved follicle developments, especially in patients with low serum CSF-1 levels in the early follicular phase. (Source: Fertility and Sterility)
Clomiphene citrate and intrauterine insemination: analysis of more than 4100 cycles
Conclusion(s): As anticipated, younger patients have a higher PR per cycle than older patients. The PR per cycle for patients who initiate only one or only two treatment cycles is notably higher than the corresponding per cycle rates for cycles 3 through 9. The drop in success per patient among 41- and 42-year-olds is sharp, but the exceptionally low success rate above age 42 suggests that CC with IUI has virtually no place in their treatment. (Source: Fertility and Sterility)
Natural history of varicocele management in the era of intracytoplasmic sperm injection
Conclusion(s): This study suggests that men with poorer baseline characteristics are more likely to opt for varicocele repair. Furthermore, couples electing not to repair the varicocele are more likely to undergo ART procedures to improve their chances of conception. (Source: Fertility and Sterility)
Artificial oocyte activation in severe teratozoospermia undergoing intracytoplasmic sperm injection
Conclusion (s): It can be concluded that in cases with severe teratozoospermia AOA may improve fertilization and cleavage rates, which in turn, affect the implantation and pregnancy rate. (Source: Fertility and Sterility)
Anti-müllerian hormone and inhibin b as predictors of pregnancy after treatment by in vitro fertilization/intracytoplasmic sperm injection
Conclusion(s): The AMH and inhibin B levels on the day of oocyte retrieval are correlated to reproductive outcome. (Source: Fertility and Sterility)
Estradiol supplementation during the luteal phase of ivf-icsi patients: a randomized, controlled trial
Conclusion(s): The addition of transdermal E2 to the luteal-phase P support of IVF cycles did not improve cycle outcomes in terms of implantation and pregnancy rates. (Source: Fertility and Sterility)
A new approach to ovarian reserve testing
Conclusion(s): Proper interpretation of screening tests for ovarian insufficiency in couples considering ART is important as the presence of impaired ovarian reserve is associated with a low likelihood of pregnancy. The condition of premature (nonphysiologic) ovarian insufficiency warrants additional research. (Source: Fertility and Sterility)
Noninvasive metabolomic profiling of embryo culture media using proton nuclear magnetic resonance correlates with reproductive potential of embryos in women undergoing in vitro fertilization
Conclusion(s): Metabolomic profile of spent embryo culture media using 1H NMR correlates with the reproductive potential of embryos. (Source: Fertility and Sterility)
Short coasting of 1 or 2 days by withholding both gonadotropins and gonadotropin-releasing hormone agonist prevents ovarian hyperstimulation syndrome without compromising the outcome
Conclusion(s): Coasting for 1 or 2 days can be used successfully to prevent OHSS without compromising IVF cycle outcome. (Source: Fertility and Sterility)
Power doppler assessment of follicle vascularity at the time of oocyte retrieval in in vitro fertilization cycles
Conclusion(s): Assessment of follicle vascularity by using PD at the time of oocyte retrieval was found to be a practical alternative to other methods. (Source: Fertility and Sterility)
Blastocyst development rate impacts outcome in cryopreserved blastocyst transfer cycles
Conclusion(s): Cryopreserved day-5 blastocysts have higher implantation rates and trend toward improved pregnancy outcomes compared with cryopreserved day-6 blastocysts. This suggests that embryo development rate may, in part, predict implantation and subsequent FBET outcomes, although embryos not achieving the blastocyst stage until day 6 still demonstrate acceptable outcomes. (Source: Fertility and Sterility)
Comparison of serum and follicular fluid hormone levels with recombinant and urinary human chorionic gonadotropin during in vitro fertilization
Conclusion(s): Recombinant and urinary hCG provided similar serum and follicular hormonal environments during the final stages of oocyte maturation. The IVF outcome parameters were also comparable. The two medications appear to be equally effective. (Source: Fertility and Sterility)
The use of estradiol for luteal phase support in in vitro fertilization/intracytoplasmic sperm injection cycles: a systematic review and meta-analysis
Conclusion(s): The addition of E2 to P4 for luteal phase support in IVF/ICSI cycles has no beneficial effect on pregnancy rates. The data in the literature are, however, limited and heterogeneous, precluding the extraction of clear and definite conclusions. A large multicenter, properly designed RCT is needed to further clarify the role of luteal E2 supplementation in IVF. (Source: Fertility and Sterility)
What is the best time to perform intracytoplasmic sperm injection/embryo transfer cycle after hysteroscopic surgery for an incomplete uterine septum?
Conclusion(s): Starting an ICSI/embryo transfer cycle just after the hysteroscopic procedure does not result in any impairment in implantation rate or PR compared to those started 10 or more weeks after the operation. (Source: Fertility and Sterility)
Early serum interleukin-8 evaluation may prove useful in localizing abnormally implanted human gestations after in vitro fertilization
Conclusion(s): In the setting of a rise or plateau in hCG levels, low day-28 IL-8 and day-35 P4 levels suggested an extrauterine implantation. This assay combination may facilitate earlier diagnosis of an ectopic gestation when pregnancy location is unclear. (Source: Fertility and Sterility)
Somali women and their pregnancy outcomes postmigration: data from six receiving countries.
Conclusions This analysis has identified a number of disparities in outcomes between Somali-born women and their receiving country counterparts. The disparities are not readily explained and they raise concerns about the provision of maternity care for Somali women postmigration. Review of maternity care practices followed by implementation and careful evaluation of strategies to improve both care and outcomes for Somali women is needed. PMID: 19035939 [PubMed - in process] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
The right to remain silent: a qualitative study of the medical and social ramifications of pregnancy disclosure for gambian women.
Conclusions Despite public health and clinical benefits of preventing and treating pregnancy infections, women were ill informed and pressurised into taking drugs. These ethical issues should be more widely addressed. PMID: 19035940 [PubMed - in process] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Author response to: reference values for clinical chemistry tests during normal pregnancy.
Author response to: Reference values for clinical chemistry tests during normal pregnancy. BJOG. 2008 Dec;115(13):1716-7 Authors: Larsson A PMID: 19035951 [PubMed - in process] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Reference values for clinical chemistry tests during normal pregnancy.
Authors: Davison J, Lind T, Lindheimer M PMID: 19035952 [PubMed - in process] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
"pregnant by choice" program provides family planning options - wyoming department of health
"Pregnant by Choice," a new Wyoming Department of Health program, will offer family planning services to new moms who are losing Wyoming EqualityCare (Medicaid) benefits at the 60-day postpartum period. (Source: Health News from Medical News Today)
The epidemiology of neuroblastoma: a review
Heck JE, Ritz B, Hung RJ, Hashibe M, Boffetta P. The epidemiology of neuroblastoma: a review. Paediatric and Perinatal Epidemiology 2008. Neuroblastoma is the most common tumour in children less than 1 year of age. The goal of this review was to summarise the existing epidemiological research on risk factors for neuroblastoma. A comprehensive search of the literature was undertaken using PubMed for epidemiological studies on neuroblastoma risk factors. We ascertained 47 articles which examined the risk factors. Ten studies employed population-based case-control designs; six were hospital-based case-control studies; two were cohort studies; and five employed ecological designs. Studies ranged in size from 42 to 538 cases. Three studies showed evidence of an increased risk of disease with us...
Anorexia nervosa and pregnancy: having a baby when you are dying to be thin - case report and proposed treatment guidelines
This report examines when to obtain a psychiatric evaluation or admission to an inpatient psychiatric unit to ensure the safety of both the woman and fetus.A case report of a pregnant woman with AN describes the risks of extreme weight loss during pregnancy and the deleterious effects on the fetus's viability and mother's health.Psychiatric intervention was not requested until late in gestation, when the patient's mental status and low weight had already deteriorated to a point of high risk to both the mother and fetus.We propose the development of treatment guidelines for the pregnant patient with AN to ensure the delivery of optimal care for both the mother and the fetus. © 2008 by Wiley Periodicals, Inc. Int J Eat Disord 2009 (Source: International Journal of Eating Disorders)
Bad science: how bbc misread the evidence on down's syndrome
As usual, it's not Watergate, it's just slightly irritating. "Down's births increase in a caring Britain," said the Times. "More babies are being born with Down's syndrome as parents feel increasingly that society is a more welcoming place for children with the condition." That's beautiful. "More mothers are choosing to keep their babies when diagnosed with Down's syndrome," said the Mail. "Parents appear to be more willing to bring a child with Down's syndrome into the world because British society has become increasingly accepting of the genetic abnormality," said the Independent.Their quoted source was a BBC Radio 4 documentary presented by Felicity Finch (her what plays Ruth Archer), broadcast on Monday. "The number of babies with Down's syndrome has steadily fallen, that is until toda...
Sierra leone: pcmh to get free emergency treatment
Pregnancy-related emergencies will soon be treated for free at the Princess Christian Maternity Hospital, the Minister of Health and Sanitation announced yesterday. (Source: AllAfrica News: Health and Medicine)
Omental trophoblastic implants after surgical management of ectopic pregnancy
Abstract  Peritoneal implants secondary to a tubal ectopic pregnancy or extratubal omental secondary trophoblastic implants (ESTI) are a rare entity often underestimated or unknown. It can be responsible of rising in the ß-hCG titer after salpingectomy for ectopic tubal pregnancy. Moreover, implants on the omentum are exceptional. This particular localization is exceptional and its physiopathology, diagnosis, surgical management and follow-up are discussed in this paper. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00404-008-0852-8Authors Dario Bucella, Erasme University Hospital, Free University of Brussels (ULB) Department of Gynaecology Brussels BelgiumFrédéric Buxant, Erasme University Hospital, Free University of Brussels (ULB) Department of Gynaec...
Helping the embryo implant: a new role for one type of immune cell
One of the most critical stages in establishing a pregnancy is the implantation of the embryo in the wall of the uterus. Although the accumulation of immune cells known as DCs has been observed in the uterus after fertilization and prior to implantation, their function was not known. (Source: ScienceDaily Headlines)
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